Determinants for deviations from guideline recommendations in cancer therapy of older patients

Determinants for deviations from guideline recommendations in cancer therapy of older patients - DELIVER

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00015495

Enrollment

750

Registered

2018-09-14

Start date

2018-10-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C18 C50 C19 C20

Interventions

Group 1: In this study adherence to clinical guidelines regarding cancer therapy will be examined in a group of patients, (= 70 yrs.) with a breast or colorectal cancer diagnosis. To investigate poten

Eligibility

Sex/Gender

All

Age

70 Years to No maximum

Inclusion criteria

Inclusion criteria: Initial diagnosis of Breast cancer or colorectal cancer, Age = 70 yrs., capacity to consent

Exclusion criteria

Exclusion criteria: lack of capacity to consent

Design outcomes

Primary

Measure	Time frame
The primary endpoint in this study is the adherence to guideline recommendations in cancer therapy of older patients. Adherence will be determined by the results of the questionnaire and by analyzing data of doctor’s clinical patient documentation. The postal survey will take place at two different time points: the first time point (t0) will be within four weeks following the diagnosis and the second time point (t1) will be six months following the diagnosis. The operationalization of factors to assess the adherence follows the actual medical S3 guidelines, (breast cancer and colorectal cancer).	—

Measure

Time frame

The primary endpoint in this study is the adherence to guideline recommendations in cancer therapy of older patients. Adherence will be determined by the results of the questionnaire and by analyzing data of doctor’s clinical patient documentation. The postal survey will take place at two different time points: the first time point (t0) will be within four weeks following the diagnosis and the second time point (t1) will be six months following the diagnosis. The operationalization of factors to assess the adherence follows the actual medical S3 guidelines, (breast cancer and colorectal cancer).

—

Secondary

Measure	Time frame
Deviations to guideline recommendations will be correlated by the following outcomes: - Quality of Life (EORTC) - Social Support (Soz-U K14) - Frailty-Index (Tilburg-Frailty-Indicator) - Self efficacy (Allgemeine Selbstwirksamkeit Kurzskala // ASKU) The results of the qualitative study will be analyzed by content analysis with a focus on barriers, interface problems, over- or undersupply. The final issue to be considered will be the thoughts of the patients, doctors and relatives regarding the course of therapy chosen, (sense or senselessness).	—

Measure

Time frame

Deviations to guideline recommendations will be correlated by the following outcomes: - Quality of Life (EORTC) - Social Support (Soz-U K14) - Frailty-Index (Tilburg-Frailty-Indicator) - Self efficacy (Allgemeine Selbstwirksamkeit Kurzskala // ASKU) The results of the qualitative study will be analyzed by content analysis with a focus on barriers, interface problems, over- or undersupply. The final issue to be considered will be the thoughts of the patients, doctors and relatives regarding the course of therapy chosen, (sense or senselessness).

—

Countries

Germany

Contacts

Public ContactSusanne Elsner

Institut für Sozialmedizin und Epidemiologie der Universität zu Lübeck

susanne.elsner@uksh.de+49 451 500 51213

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026