Imaging quality and potential clinical relevance of breast computed tomography in-vivo: a single-centre, prospective study

Imaging quality and potential clinical relevance of breast computed tomography in-vivo: a single-centre, prospective study - BreastCT

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015475

Enrollment

330

Registered

2019-05-02

Start date

2019-06-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C50

Interventions

Group 1: Imaging of the breast using a Breast CT: The new Breast CT with a high resolution is compared to conventional mammography. Patients are included who are willing to undergo both examinations.

Eligibility

Sex/Gender

Female

Age

18 Years to 110 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria - Phase 1 und 2: Patients >18 years with provided informed consent: • Patients with BI-RADS 5/6 lesions • Mastectomy or segmentectomy +/- radiotherapy planned Inclusion criteria - Phase 3: Patients >18 years with provided informed consent: • Patients registered for diagnostic or screening mammography.

Exclusion criteria

Exclusion criteria: Pregnancy, breast-feeding, re-staging after neoadjuvant chemotherapy. In phase 1 clip after biopsy

Design outcomes

Primary

Measure	Time frame
330 patients will be included to obtain the sensitivity and specificity of the breast CT compared to conventional mammography. The mammograms and the breast CT Images will be evaluated seperately by two board-certified radiologists and rated according the BI-RADS criteria.	—

Countries

Switzerland

Contacts

Public ContactNicole Berger

Universitätsspital Zürich

nicole.berger@usz.ch0041442551111

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026