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The relationship between distress and language in aphasia

The relationship between distress and language in aphasia - APHA_STRESS

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
DRKS
Registry ID
DRKS00015470
Enrollment
60
Registered
2018-10-01
Start date
2020-10-05
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R47.0

Interventions

Group 1: Phase 1a: N=30, one-armed, within-subject design. Impact of stressors (cognitive and physiological) on language-related distress and language parameters. Cross-sectional design, 1 measurement

Sponsors

Klinik für Neurologie der Uniklinik RWTH Aachen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >18 2. Informed consent 3. Diagnosed with aphasia (post-acute phase: 2-12 months post stroke/trauma or chronic phase: >12 months post stroke/trauma) 4. Situative appropriate speech perception (AAT subtest speech perception: PR > 10 or positive appraisal of speech and language therapist 5. Inward patients (specialised ward for aphasia, University Clinics Aachen)

Exclusion criteria

Exclusion criteria: 1. Non-compensability of visual impairments (e.g. neglect, hemianopsia) in the central visual field 2. Motoric or sensoric impariments on the left side of the body (in left-hemispheric stroke) 3. Psychotic, obsessive-compulsory or hypochondric disorder 4. Restrictive impairments of auditory processing; high auditive sensitivity

Design outcomes

Primary

MeasureTime frame
1. Physiological distress: heart rate variability, measured by lead of heart rate during independent variables (progressive muscle relaxation, cognitive distress, physiological distress [noise]) and dependent variables (speech production, speech perception) 2. Subjective distress: measured by changes in valence and arousal ratings (nonverbal SAM-scales) before and after IVs and DVs Measurements in Phase 1: (a) on 1 point of time (b)on three consecutive time points (cross-sectional design). Measurements in Phase 2: on three consecutive time points at the beginning and the end of the in-ward therapy, questionnaires before und after Measurements in Phase 3: on three consecutive time points before after and in between group therapies (3 times 3 measurements, 6 weeks, longitudinal design) 3. Chronic distress and related parameters: questionnaires - Depression and anxiety: Hospital Anxiety Depression Scale (HADS), Beck’s Depressionsinventory (BDI-II) - Quality of life: the Aachen inventory of quality of life (ALQI) - Distress: Stress coping inventory (SCI), Perceived Stress Questionnaire (PSQ-20), modified Perceived Stress Scale (mPSS) Measurements in Phase 1: on the first (three) consecutive time points. Measurements in Phase 2: in the first session of each measurement block: before at the beginning and the end of the in-ward therapy, questionnaires before and after the in-ward therapy. Measurements in Phase 3: in the first session of each measurement block: before after and in between group therapies

Secondary

MeasureTime frame
Speech processes in 1. Speech production (analysis of spontaneous speech, linguistic parameters) and 2. Speech perception (analysis of auditive speech perception) Measurements in Phase 1: on three consecutive time points (cross-sectional design). Measurements in Phase 2: on three consecutive time points before after and in between group therapies (3 times 3 measurements, 7 weeks, longitudinal design)

Countries

Germany

Contacts

Public ContactCharlotte Lion

Uniklinik RWTH Aachen, Klinik für Neurologie

clion@ukaachen.de0049 241 80 36641

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026