H35.7
Conditions
Interventions
Group 1: Subthreshold laser treatment with Endpoint Management. As treatment can be repeated every 3, a maximum of 4 laser treatments can be applied during the 12 months period.
Every study patient is
Sponsors
Augenklinik der Ludwig-Maximilians Universität München
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age =18 years, ability to give consent must be given, ability to participate in studies on a regular basis must be given, BCVA better than 0,05, Diagnosis of optic disc pit maculopathy, exsudative choroidal naevus, MacTel type 2 or persistent subretinal fluid after retinal detachment surgery (vitrectomy or buckling) confirmed by retinal specialist, Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
Exclusion criteria
Exclusion criteria: Any other macular disease with possibility of developing subretinal fluid: vitreomacular traction syndrome, epiretinal membranes, age-related macular degeneration, diabetic retinopathy, choroidal neovascularization, uveitis, Ocular surgery for 3 months preceding the study, Previous intravitreal injections of anti-VEGF, steroids within 3 months preceding the study, Previous macular laser treatment or photodynamic therapy within 6 months preceding the study, Present ocular infection or clinically significant inflammation, Kidney failure or dialysis, Women: Pregnancy or currently breast-feeding ,Allergy to fluorescein, History of systemic or topical corticosteroid use within last 6 months, Patient is not able to cooperate or has any other medical or psychological condition that prohibits him from regular follow-up, Planned intraocular surgery within 12 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of central subretinal fluid as measured by the decrease in central retinal thickness after 6 months (spectral-domain optical coherence tomography, SD-OCT) . | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in visual acuity (best corrected visual acuity measured by ETDRS letters), Change in retinal sensitivity as measured by microperimetry, Change in Ellipsoid-Zone Defect as measured by En-face-OCT after 12 months | — |
Countries
Germany
Contacts
Public ContactBenedikt Schworm
Augenklinik der Ludwig-Maximilians-Universität München
Outcome results
None listed