T86.1
Conditions
Interventions
Group 1: Investigation of serum and urine among patients with kidney allograft without rejection and without CMV- or BKV-infection on one examination day
Group 2: Investigation of urine and serum amon
Sponsors
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt am Main
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Group A: Men and women over the age of 18, who receive a kidney allograft and have no signs for rejection. The earliest inclusion date is four weeks after kidney transplantation. Group B: Men and women over the age of 18, who receive a kidney allograft and have a rejection, which is confirmed by a kidney biopsy Group C: Men and women over the age of 18, who receive a kidney allograft and suffer from a CMV- or BKV-infection Group D: Men and women over the age of 18, after de novo kidney transplantation Group K: Healthy men and healthy women over the age of 18, who don’t receive a kidney allograft
Exclusion criteria
Exclusion criteria: exclusion criteria arise from inclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint of the study is the recording of the concentrations of the following molecules in the blood and urine of the study participants: CXCL9, CXCL10, CCL2, CCL5, IL-37 and IL-38. If additional potential biomarkers are investigated among the study participants, the recording of the concentrations of these additional potential biomarkers will be the primary endpoint. | — |
Secondary
| Measure | Time frame |
|---|---|
| non-existent | — |
Countries
Germany
Contacts
Public ContactIngeborg A. Hauser
Medizinische Klinik III - Funktionsbereich Nephrologie Universitätsklinikum Frankfurt
Outcome results
None listed