EFFECT OF RED YEAST RICE ON COGNITIVE FUNCTIONING IN SCHIZOPHRENIA.

EFFECT OF RED YEAST RICE ON COGNITIVE FUNCTIONING IN SCHIZOPHRENIA. - RYRCOG

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015300

Enrollment

Registered

2018-09-07

Start date

2017-05-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

DSM-5 295.90 F20.9

Interventions

Group 1: Thirty-five schizophrenia outpatients (age range: 18-60 yrs) on stable antipsychotic treatment and assessed by neuropsychological (WCST, Verbal Fluency, and Stroop task) and psychodiagnostic

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients (aged 18-60 years) affected by schizophrenia on stable SGAs therapy for at least three months.

Exclusion criteria

Exclusion criteria: Mental retardation, alcohol/drug dependence, organic brain disorder, pregnancy/lactation, and any major concomitant medical illnesses.

Design outcomes

Primary

Measure	Time frame
Investigate the effects of red yeast rice therapy on cognitive/executive functioning in schizophrenia patients treated with antipsychotics. Data for cognitive/executive functioning assessments were measured at baseline and and week-12 with the Wisconsin Card Sorting Test (WCST), the Verbal Fluency Task (Controlled Oral Word Association Test), and the Stroop Colour-word Test; clinical symptoms were evaluated by the Brief Psychiatric Rating Scale (BPRS).	—

Measure

Time frame

Investigate the effects of red yeast rice therapy on cognitive/executive functioning in schizophrenia patients treated with antipsychotics. Data for cognitive/executive functioning assessments were measured at baseline and and week-12 with the Wisconsin Card Sorting Test (WCST), the Verbal Fluency Task (Controlled Oral Word Association Test), and the Stroop Colour-word Test; clinical symptoms were evaluated by the Brief Psychiatric Rating Scale (BPRS).

—

Secondary

Measure	Time frame
Investigate the safety of red yeast rice supplementation in a sample of schizophrenia subjects.	—

Countries

Italy

Contacts

Public ContactMaria Rosaria Anna Muscatello

Psychiatric Unit, AOU. Policlinico "G. Martino"

mmuscatello@unime.it00390902212092

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026