Expiratory flow limitation via 'Flow-Limiter': A feasability study wth spontaneously breathing, lung healthy volunteers

Expiratory flow limitation via 'Flow-Limiter': A feasability study wth spontaneously breathing, lung healthy volunteers - Flow Limiter with volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015296

Enrollment

Registered

2018-08-20

Start date

2018-08-27

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Modulation of the expiration during spontanous breathing comparable to pursed lip breathing lung healthy volunteers

Interventions

Group 1: Cross over design. After baseline measurement of the expiratory flow, the flow will be limited in two steps (ca. 30% and ca. 60%

3 min. each

randomised sequence). Group 2: see Arm 1

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: lung healthy

Exclusion criteria

Exclusion criteria: known cardiocirculatory diseases, known lung diseases, pregnancy, active implants

Design outcomes

Primary

Measure	Time frame
Tolerable expiratory flow limitation, rated by the volunteer directly after the experiment.	—

Secondary

Measure	Time frame
Expiratory peak flow, measured by pneumotachography as mean for the duration of the experiment. Regional ventilation, measured by electrical impedance tomography as a mean for the duration of the experiment. Subjective perception, rated by the volunteer as forced choice (better/worse), directly after the experiment.	—

Countries

Germany

Contacts

Public ContactJohannes Schmidt

Klinik für Anästhesiologie und Intensivmedizin Universitätsklinikum Freiburg

johannes.schmidt@uniklinik-freiburg.de+49 761 270 23060

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 9, 2026