Intervention study on the effect of oyster mushrooms as part of a meal on glucose and lipid metabolism, hunger and satiety in adults with impaired glucose tolerance

Intervention study on the effect of oyster mushrooms as part of a meal on glucose and lipid metabolism, hunger and satiety in adults with impaired glucose tolerance - PleurO-study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015244

Enrollment

Registered

2018-08-09

Start date

2018-12-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R73.0

Interventions

Group 1: 20 g oven-dried, powdered oyster mushrooms ingested within a carbohydrate-rich meal

at least 1 week washout between the consumption of meals with and without mushrooms Group 2: carbohydrate-rich meal without mushrooms

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Impaired glucose tolerance according to national and international guidelines (2-h-glucose concentration after OGTT between 140-199 mg/dl), nonsmoker for at least 3 months, written informed consent

Exclusion criteria

Exclusion criteria: Intake of drugs that may affect primary or secondary outcome measures; intake of antibiotics within the last 6 weeks; hepatic and gastrointestinal diseases accompanied with diarrhea and malabsorption; allergies, intolerances and aversions against mushrooms and components of the test meal; cardiac pacemaker or other implantable electronic devices; pregnancy/lactation; planned changes in lifestyle (e.g. by diet); regular consumption of foods or supplements rich in ß-glucans

Design outcomes

Primary

Measure	Time frame
Glucose-AUC (Area under the curve), based on glucose concentration in sodium fluorid plasma which will be determined before and 15, 30, 45, 60, 90, 120, 180 and 240 min after meal consumption	—

Secondary

Measure	Time frame
Gucose metabolism (insulin in serum, GIP and GLP-1 in EDTA-plasma), lipid metabolism (triglycerides and non-esterified free fatty acids in serum), hunger and satiety (determined by means of visual analog scales; ghrelin in EDTA-plasma); determination before as well as 15, 30, 45, 60, 90, 120, 180 and 240 min after meal consumption	—

Countries

Germany

Contacts

Public ContactLisa Dicks

Hochschule Niederrhein, Fachbereich Oecotrophologie

Lisa.Dicks@hs-niederrhein.de02161-186-5397

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 21, 2026