A randomized controlled clinical trial comparing small buccal dehiscence defects around dental implants treated with an autogenous connective tissue graft (SCTG) or with standard guided bone regeneration (GBR).

A randomized controlled clinical trial comparing small buccal dehiscence defects around dental implants treated with an autogenous connective tissue graft (SCTG) or with standard guided bone regeneration (GBR). - SCTG vs GBR

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015194

Enrollment

Registered

2018-10-24

Start date

2019-02-13

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Missing tooth in the posterior area (premolar or molar)

Interventions

Group 1: Testgroup: Subepithelial connective tissue graft (SCTG) from the palate Group 2: Controlgroup: Guided bone regeneration (GBR), using Bio-Oss® Spongiosa Granules und Bio-Gide® membrane, Geistl

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Signed informed consent form 2. Need of implant placement in posterior area (premolar or molar, mandible or maxilla) 3. Periodontal healthy patients (periodontal probing depths 6 weeks after tooth extraction 6. A dehiscence defect (= 3 mm) after implant placement 7. At least one neighboring tooth present

Exclusion criteria

Exclusion criteria: 1. Pregnant and lactating female patient 2. Known or suspected non-compliance, drug or alcohol abuse 3. Inability to follow the procedures of the study, 4. Smoking > 15 cigarettes a day

Design outcomes

Primary

Measure	Time frame
Tissue volume changes in horizontal dimensions between baseline (before implant placement) and at 4 month post implant placement. The changes will be evaluated based on scans of the impressions.	—

Secondary

Measure	Time frame
Secondary endpoints will be assessed 3 years after Crown insertion (Baseline 2): - Buccal tissue changes - Margo mucosae level: using a periodontal probe - Clinical measurements: KT (width of keratinized tissue), PD (pocket depth), REC (recession), BOP (bleeding on probing), Pl (plaque index) - Relative contour increase: using CBCT scans - Patient related outcome measures (PROMs): using questionnaires	—

Measure

Time frame

Secondary endpoints will be assessed 3 years after Crown insertion (Baseline 2): - Buccal tissue changes - Margo mucosae level: using a periodontal probe - Clinical measurements: KT (width of keratinized tissue), PD (pocket depth), REC (recession), BOP (bleeding on probing), Pl (plaque index) - Relative contour increase: using CBCT scans - Patient related outcome measures (PROMs): using questionnaires

—

Countries

Switzerland

Contacts

Public ContactDaniel Thoma

Universität Zürich, Zentrum für Zahnmedizin, Klinik für Rekonstruktive Zahnmedizin

research.rzm@zzm.uzh.ch+41 44 634 04 04

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026