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Outcome of pregnancies exposed to the selective progesterone receptor modulator ulipristal acetate - Evalutation of the national Embryotox cohort

Outcome of pregnancies exposed to the selective progesterone receptor modulator ulipristal acetate - Evalutation of the national Embryotox cohort

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00015155
Enrollment
200
Registered
2018-07-25
Start date
2018-07-09
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Q89.9 O03

Interventions

Group 1: Evaluation and description of pregnancy- outcomes after failed postcoital contraception with UPA (ulipristal acetate) (single dose 30 mg/d) or after Uterus myomatosus-treatment (daily 5 mg/d)

Sponsors

Pharmakovigilanzzentrum Embryonaltoxikologie Charité-Universitätsmedizin
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Unintended pregnancies after postcoital contraception with UPA or myoma-therapy

Exclusion criteria

Exclusion criteria: None.

Design outcomes

Primary

MeasureTime frame
Description and evaluation of: a) congenital birth defects after exposure to the study medication during 1st trimester. b) spontaneous abortions, elective terminations of pregnancy and other adverse pregnancy outcomes after exposure to the study medication at any time during pregnancy. Using a structured questionnaire, at first contact with our institute all relevant data are documented. 8 weeks after the expected date of delivery follow-up is conducted using a mailed questionnaire covering complications of pregancy or delivery, pediatric check up, and congenital anomalies. Final endpoint will be June 2021.

Secondary

MeasureTime frame
Description and determination of a) possible reasons for failed emergency contraception, e.g. because of maternal characteristics (high BMI) or inadequate application time b) possible reasons for failed medical termination of pregnancy

Countries

Germany

Contacts

Public ContactJenny Katharina Wagner

Pharmakovigilanzzentrum Embryonaltoxikologie Charité-Universitätsmedizin Berlin

jenny-katharina.wagner@charite.de030450525702

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 19, 2026