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Development of a Risk Prediciton Model for Chemotherapy-induced Nausea and Vomiting

Development of a Risk Prediciton Model for Chemotherapy-induced Nausea and Vomiting - EmRISK / NOGGO S18

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00015151
Enrollment
519
Registered
2018-10-09
Start date
2019-05-22
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynaecological cancer

Interventions

Group 1: Standard chemotherapy
during therapy nausea and vomiting will be recorded via patient questionnaires and daily diary. No interventions will be performed.

Sponsors

NOGGO e.V. Nord-Ostdeutsche Gesellschaft für Gynäkologische Onkologie
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Diagnosis with primary gynaecological cancer and/or breast cancer - Planned chemotherapy for at least three cycles, adjuvant and neoadjuvant (as standard of care)

Exclusion criteria

Exclusion criteria: - Chemotherapy has already started - Tumour of a different origin - Metastases in the central nervous system - Bowel obstruction/ Ileus/ Subileus

Design outcomes

Primary

MeasureTime frame
Primary endpoint is prediction of CINV within the first three cycles and evaluation of a risk score; after first phase of the study and data evaluation the risk score will be assessed and tested in the 2nd study phase

Secondary

MeasureTime frame
- Incidence and NCI-CTC grade of AE, - Dose reduction, - Delay of therapy, - Early termination of therapy and the reasons, - Quality of life and the development of it from baseline to 3rd and 6th cycle

Countries

Germany

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Apr 4, 2026