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A speech-gesture-training for patients with schizophrenia and its neural correlates – a randomized controlled trial with follow-up

A speech-gesture-training for patients with schizophrenia and its neural correlates – a randomized controlled trial with follow-up - G+

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00015118
Enrollment
60
Registered
2018-08-27
Start date
2017-11-23
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20 F25 F21

Interventions

Group 1: wait-training group: patients as well as healthy controls first get treatment as usual (TAU), and then the speech gesture training in the following order: 1st pre fMRI - TAU - 2nd pre fMRI -

Sponsors

Universitätsklinikum Gießen und Marburg, Standort Marburg, Klinik für Psychiatrie und Psychotherapie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 62 Years

Inclusion criteria

Inclusion criteria: Diagnosis of schizophrenia or schizoaffective disorder (for patients) and relatively stable symptoms (no acute psychosis), Aged between 18 and 60 years, Capacity to give informed consent

Exclusion criteria

Exclusion criteria: No capacity to give informed consent, Risk of suicide necessitating hospitalisation, Physical illnesses that interfere with the planned measurements, Medical contraindication against fMRI measurements, Pregnancy, Contraception per loop, Diagnosis of psychological diseases, especially schizophrenia (for control group)

Design outcomes

Primary

MeasureTime frame
neural data in comparison of groups and pre post fMRI measurement (before and after the training) of the applied tasks (passive viewing and n-back working memory task)

Secondary

MeasureTime frame
behavioral data from working memory tasks in comparison of groups and pre post fMRI measurements (before and after the training) as well as transfering effects (assessed by SASS: Soziale Aktivität Selbstbeurteilungs-Skala and SWLS: Satisfaction with Life Scale). Separate comparisons of neural activation during processing of speech, gesture and speech-related gestures during the passive viewing and working memory task.

Countries

Germany

Contacts

Public ContactLydia Riedl

Universitätsklinikum Marburg-Gießen, Standort Marburg, Klinik für Psychiatrie und Psychotherapie

Riedll@staff.uni-marburg.de+491601112537

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 21, 2026