Influence of beta blockers and night time pacing frequencies of implanted cardiac devices (PM, CRT, ICD) on overnight blood gas transport capacity

Influence of beta blockers and night time pacing frequencies of implanted cardiac devices (PM, CRT, ICD) on overnight blood gas transport capacity - NBGTC

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015100

Enrollment

Registered

2018-07-27

Start date

2018-06-29

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J96.1

Interventions

Group 1: Patients with established beta blocker therapy with additional night time bradycardia and coexisting night time hypercapnia. Intervention: Stepwise discontinuation of beta blocker therapy wit

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Hypercapnia under established beta blocker therapy or established therapy by implanted cardiac devices (PM, CRT, ICD) or persistent hypercapnia under NIV therapy and established beta blocker therapy or established therapy by implanted cardiac devices (PM, CRT, ICD)

Exclusion criteria

Exclusion criteria: 1. aortic valve insufficiencies, 2. artrial fibrillation, 3. ejection fraction <40%, 4. high amount of ventricular extra systoles, 5. instable coronary heart disease, 6. tachycardic supraventricular and ventricular arrhythmias, 7. Myokard infarktion < 6 Monate, 8. hypertensive blood pressure situation

Design outcomes

Primary

Measure	Time frame
night time pCO2 reached normal values	—

Secondary

Measure	Time frame
night time hypercapnia is persistent	—

Countries

Germany

Contacts

Public ContactJens Kerl

Fachkrankenhaus Kloster Grafschaft GmbH

j.kerl@fkkg.de02972-7911703

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026