healthy sujects
Conditions
Interventions
Group 1: Study Day 1:
250 ml of decaffeinated coffee (placebo control)
Group 2: Study Day 2:
250 ml decaffeinated coffee + 150 mg caffeine
Group 3: Study Day 3:
250 ml decaffeinated coffee + 10 g MCT
Sponsors
Fachhochschule Münster
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Age between 18 - 30 years, male, female (equal distribution), no known metabolic disease (eg disturbance of lipid metabolism, diabetes mellitus type 1 or 2), no intake of medication (exception: contraceptives), no chronic health impairment (eg cardiovascular diseases, thyroid defects, intestinal diseases), no mental or linguistic limitations, No low carbohydrate, vegan or other diet with permanent reduction of carbohydrate intake (references of the German Nutrition Society: at least 50% carbohydrate), Signature of the consent form, Non smoking
Exclusion criteria
Exclusion criteria: Ingestion of nutritional supplements with effects on lipid metabolism (eg MCT), Pregnancy / Breastfeeding, simultaneous participation in other studies / study programs, taking medication (exeption:contraceptives), severe underlying disease (eg cancer), mental illnesses (eg depression, schizophrenia), existing disease of the metabolism, chronic illness, lower deviations from the references of the German Nutrition Society for healthy mixed food (<50% carbohydrate / day), Blood donation within the last 3 months before the start of the study, Incompatibility with MCT and / or caffeine, smoker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ß-hydroxybutyrate (mmol/L) in capillary blood at t0 (baseline) and tmax (primary outcome). Measuring over a period of 4 hours every 40 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| tolerability (self documentation of the subjects, during intervention time), sensory interview (description of taste, odor, mouthfeel during intake of test solution), blood parameters: glucose (every 40 minutes over 4 h), respiratory measurement: acetone, saliva analysis: caffeine, theobromine, theophylline, Urinalysis: caffeine, urine test strips (leucocytes, nitrite, pH, protein, glucose, ketone, urobilinogen, bilirubin, blood) | — |
Countries
Germany
Contacts
Public ContactAnna Baumeister
Fachhochschule Münster
Outcome results
None listed