Healthy volunteers
Conditions
Interventions
Group 1: Included test persons are subjected to the following examinations:
- Collection of a plasma sample (equivalent to approx. 15 ml whole blood) from a peripheral vein
- Delivery of a urine samp
Sponsors
Universitätsklinikum Bonn
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - age of >18 years - Ability to give legal consent - male sex (inability to become pregnant) - informed written consent
Exclusion criteria
Exclusion criteria: Answer one of the following questions with "Yes": - Do you regularly take medication? - Do you have an acute or chronic disease? - Do you have or are you suffering from an addiction disorder of any kind (alcohol, medication, drugs)? - Are you feeling sick? - Any complaints after a previous blood withdrawal (fainting, infections, etc.)? - Have you ever had any problems with red wine (consumed in the usual quantities)?
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resveratrol plasma concentration 60 min after ingestion of the test fluid compared to baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| - Resveratrol urine concentration 120 min after ingestion of test fluid compared to baseline - Hemodynamics (HF, RR) 60 min after ingestion of test fluid compared to baseline - Brachial artery diameter sonographically 60 min after ingestion of the test fluid compared to baseline - microvascular reactivity 60 min after ingestion of test fluid compared to baseline | — |
Countries
Germany
Contacts
Public ContactTobias Hilbert
Universitätsklinikum Bonn
Outcome results
None listed