Time-Restricted Feeding for the Prevention and Therapy of Lifestyle-dependent Disease

Time-Restricted Feeding for the Prevention and Therapy of Lifestyle-dependent Disease - TRF-Pilot

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00015057

Enrollment

Registered

2018-08-10

Start date

2018-09-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention and therapy of lifestyle-dependent disease

Interventions

Group 1: Intervention in Healthy participants: restriction of the daily intake of solid food to 8-9 hours is carried out for a period of three months. Group 2: Intervention in patients with any compon

Eligibility

Sex/Gender

All

Age

18 Years to 67 Years

Inclusion criteria

Inclusion criteria: Arm 1: Employees of the University/University Hospital Ulm, no known metabolic diseases, no known eating disorders. Arm 2: Patients of the GP's practice with characteristics of metabolic syndrome without eating disorders, no insulin-dependent diabetes, no hyperthyroidism

Exclusion criteria

Exclusion criteria: Contraindications for fasting

Design outcomes

Secondary

Measure	Time frame
Secondary outcome measures are longitudinal changes in anthropometric parameters (height, weight, waist circumference) and laboratory parameters (fasting glucose, IGF-1, triglycerides, cholesterol, HDL, LDL, cortisol, LDH, CRP) as well as health-related quality of life (VAS from EQ-5D), sleep duration and quality. These data are collected at the two measurement points before and after the intervention.	—

Measure

Time frame

Secondary outcome measures are longitudinal changes in anthropometric parameters (height, weight, waist circumference) and laboratory parameters (fasting glucose, IGF-1, triglycerides, cholesterol, HDL, LDL, cortisol, LDH, CRP) as well as health-related quality of life (VAS from EQ-5D), sleep duration and quality. These data are collected at the two measurement points before and after the intervention.

—

Primary

Measure	Time frame
Primary outcome measure is the achievement of the target period of 8-9 hours of food intake (recorded in a diary: time of first and last meal). For this purpose, the percentage of days with the achievement of the target over the entire study period is calculated for each participant.	—

Countries

Germany

Contacts

Public ContactDorothea Kesztyüs

Institut für Allgemeinmedizin, Universität Ulm

dorothea.kesztyues@uni-ulm.de0731/500 31102

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 17, 2026