Pneumothorax rates in neurosurgical patients with infraclavicular subclavian catheterization. A comparison of continued mechanical ventilation to apnea during puncture: A prospective, randomized, controlled non-inferiority trial

Pneumothorax rates in neurosurgical patients with infraclavicular subclavian catheterization. A comparison of continued mechanical ventilation to apnea during puncture: A prospective, randomized, controlled non-inferiority trial - Subclavian CVC and ventilation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00014941

Enrollment

2060

Registered

2018-06-19

Start date

2014-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infraclavicular subclavian catheterization J95.80

Interventions

Group 1: Intervention Group 1: "Ventilation" The puncture is carried out with continued ventilation: Tidal volume 7 ml / kg ideal body weight (IBW

= height - 100) • Respiratory rate 10 min-1 • PEEP IBW / 10 mbar • oxygen concentration after oxygen saturation Group 2: Intervention Group 2: "Apnea" The puncture is performed with suspended ventilat

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • An elective intracranial intervention with the necessity of a CVC. • Written informed consent of the patient

Exclusion criteria

Exclusion criteria: • infections or anatomical abnormalities at the puncture site • history of clavicle fracture • Pregnancy • Neurological disorders with a lack of self-determination

Design outcomes

Primary

Measure	Time frame
Postoperative pneumothorax rate (Sonographic detection/ exclusion of a pneumothorax with image evidence (acoustic window: ventral: 3rd-4th ICR medioclavicular with image documentation) or chest radiography within the first 24h postoperatively	—

Secondary

Measure	Time frame
• Hit rate at the first puncture • Number of punctures to success • Number of arterial punctures • Failure and changing the puncture site	—

Countries

Germany

Contacts

Public ContactThomas Palmaers

Klinik für Anästhesiologie und IntensivmedizinMedizinische Hochschule Hannover

palmaers.thomas@mh-hannover.de+49 (0) 511/532 2294

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026