F90
Conditions
Interventions
Group 1: This is a non-interventional study (EEG, neuropsychological testing, interview), which is independent of the clinical drug treatment with methylphenidate.
Amendment 1: unmedicated adult pati
Sponsors
Klinik für Psychiatrie und Psychotherapie der Uniklinik Köln
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Amendment 1+2: 1) Age 18-45 2) Sufficient understanding of the German language for the questionnaire survey 3) Written informed consent of patients 4) Diagnosis of ADHD according to ICD-10 5) Clinically indicated treatment with methylphenidate 6) Stable psychotropic medication (except ADHD medication) for at least 4 weeks Amendment 1: unmedicated, concerning methylphenidate Amendment 2: Medicated for at least 6 months with methylphenidate
Exclusion criteria
Exclusion criteria: 1. known neurological disorders affecting the brain, including condition after craniocerebral trauma with unconsciousness greater than 5 minutes 2. harmful substance use according to ICD-10 3. taking antipsychotics up to 4 weeks before baseline and during the examination period For Amendment 1: 4. taking pharmaceuticals for ADHD treatment on the day of the examination (not extended release) or within 48 hours (extended release and atomoxetine) before baseline For Amendment 2: 4. taking pharmaceuticals for ADHD treatment on the day of the examination (not extemded release) or within 48 hours (extended release and atomoxetine) before baseline, with the exception of methylphenidate 5. motor hyperactivity at the time of measurement that makes an EEG examination impossible 6. known IQ < 70 7. premature birth < 32 wks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evidence of specific changes in the EEG relative to medication | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationship between EEG parameters, dosage of medication, neuropsychology and interviews on the current condition (ADHS-E, Wender Utah Rating Scale short form (WURS-K), Wender-Reimherr-Interview (WRI-V), Testbatterie zur Aufmerksamkeitsprüfung (TAP)) | — |
Countries
Germany
Contacts
Public ContactRalf Müller
Klinik für Psychiatrie und Psychotherapie der Uniklinik Köln
Outcome results
None listed