Microbiological dynamics of red complex bacteria following full-mouth air polishing in periodontally healthy subjects – a randomized clinical pilot study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

DRKS

Registry ID

DRKS00014834

Enrollment

Registered

2018-06-12

Start date

2011-04-11

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.3

Interventions

Group 1: periodontally healthy individuals receive supragingival debridement alone Group 2: periodontally healthy individuals receive supragingival debridement with adjunct full-mouth glycine powder a

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: -periodontal health -the intraoral detection of at least one periodontal pathogen - adult individuals aged 18 years or older

Exclusion criteria

Exclusion criteria: - systemic disease (e.g. Diabetes mellitus) - intake of any medication affecting the oral microbial flora - intake of antibiotics within the last 3 months prior to the study - pregnancy or lactating period - persisting oral mucosal disease

Design outcomes

Primary

Measure	Time frame
Aim: Eradication of periodontal pathogens, predefined maximum observation period of three months starting immediately after treatment. Microbiological sampling 2, 5 and 9 days after treatment. Verification of periodontal pathogens by PCR. If at least one of the previously proven periodontal pathogens is still not detectable after 9 days additional appointments for microbiological sampling were scheduled 6 weeks and three months after treatment.	—

Measure

Time frame

Aim: Eradication of periodontal pathogens, predefined maximum observation period of three months starting immediately after treatment. Microbiological sampling 2, 5 and 9 days after treatment. Verification of periodontal pathogens by PCR. If at least one of the previously proven periodontal pathogens is still not detectable after 9 days additional appointments for microbiological sampling were scheduled 6 weeks and three months after treatment.

—

Countries

Germany

Contacts

Public ContactThomas Beikler

Poliklinik für Zahnerhaltung und Präventive Zahnheilkunde Universitätsklinikum Hamburg Eppendorf/UKE

t.beikler@uke.de+49 (0) 40 7410 - 52282

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026