Validation of a Propofol Detector (EDMON) for Anesthesia during a Single Lung Ventilation (SLV) Surgery

Validation of a Propofol Detector (EDMON) for Anesthesia during a Single Lung Ventilation (SLV) Surgery - EDMON-ELV

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00014788

Enrollment

Registered

2018-06-04

Start date

2018-06-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing lung surgery with single-lung ventilation

Interventions

Group 1: The exhaled air of patients undergoing pulmonary surgery with single-lung ventilation (SLV) and propofol anesthesia will be evaluated intraoperatively for the propofol concentration using the

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Written consent of the patient; Patients undergoing elective surgery for general anesthesia who require single-lung ventilation for surgical reasons; an arterial cannula is required for the procedure and / or postoperative care; Age = 18 years; ASA I-III; No significant hepatic, nephrological, neurological and cardiac pre-existing conditions; BMI <35; No participation in another study (up to 30 days before enrollment in the study); In women of childbearing potential: negative pregnancy test, or surgical sterilization or contraceptive use during the examination or min. 2 years after postmenopause

Exclusion criteria

Exclusion criteria: Contraindications or known intolerance to any of the medicines or procedures used; Pre-existing conditions or patient circumstances that make it impossible or meaningless to examine the patient (for example, dementia, psychiatric disorders, lack of understanding of speech or ability to speak); Patients with significant cardiac pre-existing conditions; Body Mass Index > 35; ASA status> III; drug abuse; Positive HIV or hepatitis test; Pregnancy; Rejection by the patient

Design outcomes

Primary

Measure	Time frame
Determination of propofol concentration in the exhaled air during one-lung ventilation (ELV) compared to two-lung ventilation	—

Secondary

Measure	Time frame
Comparison of propofol concentration in exhaled air during one-lung ventilation (ELV) versus blood plasma concentration.	—

Countries

Germany

Contacts

Public ContactTobias Hüppe

Center of Breath Research Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie Universitätsklinikum des Saarlandes

tobias.hueppe@uks.eu+4968411622736

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 10, 2026