Changes in sleep architecture in German Armed Forces personnel with posttraumatic stress disorder compared with depressed and healthy control subjects

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00014762

Enrollment

141

Registered

2018-06-13

Start date

2014-12-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F43.1 F32.1

Interventions

Group 1: Not only soldiers with deployment-related trauma were included in this study, but also those who developed PTSD with no (obvious) military context in accordance with ICD-10 diagnostic criteri

Eligibility

Sex/Gender

All

Age

21 Years to No maximum

Inclusion criteria

Inclusion criteria: A consecutive sample of patients with an ICD-10 diagnosis of posttraumatic stress disorder (F43.1) or depression (F32, F33) were recruited from the pool of regular inpatients at the Mental Health Centre at Bundeswehr Hospital Hamburg. Not only soldiers with deployment-related trauma were included in this study, but also those who developed PTSD with no (obvious) military context in accordance with ICD-10 diagnostic criteria.

Exclusion criteria

Exclusion criteria: The following exclusion criteria were determined on the basis of ICD-10: psychotic disorder (F20-F29), manic episode, bipolar affective disorder (F30, F31), personality disorders (F60-F69), alcohol and/or drug addiction (F10-F19), neurological disease involving the central nervous system, sleep apnoea and other organic sleep disorders (G47.-) as well as nonorganic sleep disorders (F51.-) other than nightmares (F51.5). Furthermore, we excluded subjects who had been diagnosed with a comorbidity of the respective other group (i.e. PTSD or depression).

Design outcomes

Primary

Measure	Time frame
The effects of group membership, medication and group x medication interaction were analysed for the following variables: sleep onset latency, REM sleep latency, slow-wave sleep and REM sleep percentages. Polysomnography The device used in this study for sleep monitoring was the Somnowatch TM plus ®. It includes a 6-channel electroencephalogram (F3, F4, C3, Cz, C4, P3, P4), an electromyogram to monitor muscle tone, an electrooculogram to track eye movements and actigraphy to monitor body positions and movements. Using this device, we can differentiate between REM sleep stages, sleep stage 1, sleep stage 2 and slow-wave sleep and determine their percentages of sleep duration and sequence throughout the sleep cycle.	—

Measure

Time frame

The effects of group membership, medication and group x medication interaction were analysed for the following variables: sleep onset latency, REM sleep latency, slow-wave sleep and REM sleep percentages. Polysomnography The device used in this study for sleep monitoring was the Somnowatch TM plus ®. It includes a 6-channel electroencephalogram (F3, F4, C3, Cz, C4, P3, P4), an electromyogram to monitor muscle tone, an electrooculogram to track eye movements and actigraphy to monitor body positions and movements. Using this device, we can differentiate between REM sleep stages, sleep stage 1, sleep stage 2 and slow-wave sleep and determine their percentages of sleep duration and sequence throughout the sleep cycle.

—

Countries

Germany

Contacts

Public ContactRobert Gorzka

Bundeswehrkrankenhaus Hamburg

robertgorzka@bundeswehr.org040-694726440

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026