Aquired von-Willebrand-Syndrome in Pediatric Cardiac Surgery

Aquired von-Willebrand-Syndrome in Pediatric Cardiac Surgery - AWISPECS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00014723

Enrollment

Registered

2018-05-07

Start date

2018-03-01

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D68.01

Interventions

Group 1: Patients 50mmHg, Surgery on Cardiopulmonary Bypass (CPB). Measurement times: 1. before surgery, 2. after end of CPB, 3. on the 1st postopative day and 4. before discharge. 2ml blood for each

Eligibility

Sex/Gender

All

Age

0 Days to 12 Months

Inclusion criteria

Inclusion criteria: Necessity of Cardiac Surgery or surgery of the great Arteries

Exclusion criteria

Exclusion criteria: Surgical bleeding with the need of Reoperation (e.g. patch rupture) Innate von Willebrand Syndrome

Design outcomes

Primary

Measure	Time frame
Incidence of AVWS (aquired von Willebrand syndrome). Each blood sample (4 in total / patient) will be tested for AVWS using multimer analysis. For each time point (pre-, intra- and postoperative), the incidence of AVWS will be regarded and reported separately.	—

Secondary

Measure	Time frame
Factors influencing the development of AVWS (aquired von Willebrand syndrome) For each time point of blood collection (pre-, intra- and postoperative), the incidence of AVWS will be regarded separately and correlated with the corresponding echogradients / heart defects. In addition, the HLM times are evaluated.	—

Countries

Germany

Contacts

Public ContactVanya Icheva

Universitäts-Kinderklinik Tübingen

vanya.icheva@med.uni-tuebingen.de070712981329

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026