F42
Conditions
Interventions
Group 1: Patients with obsessive-compulsive disorder
- psychopathologic questionnaires (disorder-specific, e.g. YBOCS)
- EEG paradigms (Patch-leaving, Task switching)
Patients with obsessive-compulsiv
Sponsors
Universitätsklinikum Köln
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: - Patient approves to be evaluated - Patients have to be capable to give consent - Written informed consent
Exclusion criteria
Exclusion criteria: - clinical relevant psychiatric disorder - severe and instable physical disorder and brain tumors - clinical relevent internal or neurological disorder - pregnancy or breast feeding - suicidal tendencies or violent behavior in the last 4 weeks - acute psychotic symptoms - current sedative medication with benzodiazepines - hospitalization according to PsychKG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We observe cognitive flexibility especially action adaptation using a Task switching paradigm. A switch between cognitive tasks is associated with switching-costs. Higher switching-costs are designated by prolonged reaction times and are an indicator for decreased cognitive flexibility. We plan a comparison of the switching-costs and the associated electrophysiological potentials (P3) between patients with OCD, DBS-patients with OCD (acute effect of the on/off condition), and healthy controls. | — |
Secondary
| Measure | Time frame |
|---|---|
| Parameters of the patch-leaving task. We plan a comparison between patients with OCD, DBS-patients with OCD (acute effect of the on/off condition), and healthy controls, including the associated electrophysiological potentials. | — |
Countries
Germany
Contacts
Public ContactElena Sildatke
Uniklinik Köln; Klinik für Psychiatrie und Psychotherapie
Outcome results
None listed