ProHEAD – Promoting Help-seeking using E-technology for Adolescents. Sub-project 4: Efficacy and cost-effectiveness of two online interventions for children and adolescents at risk for depression

ProHEAD – Promoting Help-seeking using E-technology for Adolescents. Sub-project 4: Efficacy and cost-effectiveness of two online interventions for children and adolescents at risk for depression - E.motion trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00014668

Enrollment

363

Registered

2018-05-04

Start date

2018-11-21

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive symptoms, subthreshold depression F32

Interventions

Group 1: This randomized-controlled trial is part of the ProHEAD project (Promoting Help-seeking using E-technology for ADolescents) aiming to assess new access pathways for prevalent mental health pr

Eligibility

Sex/Gender

All

Age

12 Years to 19 Years

Inclusion criteria

Inclusion criteria: Current subthreshold depressive symptoms, operationalized with the Patient Health Questionnaire-9 modified for Adolescents (PHQ-A; Johnson, Harris, Spitzer & Williams, 2002) with sum scores in the range of 10 – 14; sufficient German language skills; internet access

Exclusion criteria

Exclusion criteria: PHQ-A sum score 14; current suicidal intents according to the PHQ-A; other current mental health problems as identified by scoring above the clinical cut-off in one or more of the following questionnaires: Strengths and Difficulties Questionnaire (SDQ; Goodman, Meltzer, & Bailey, 1998), Short Evaluation of Eating Disorders (SEED; Bauer, Winn, Schmidt, & Kordy, 2005), Weight Concerns Scale (WCS; Killen et al., 1996), Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT-d; Tossmann, Kasten, Lang, & Struber, 2009) and Alcohol Use Disorders Identification Test (AUDIT; Babor, Higgins-Biddle, Saunders, & Monteiro, 2001)

Design outcomes

Primary

Measure	Time frame
Depression symptomatology at the end of intervention (measured by the Patient Health Questionnaire-9 modified for Adolescents [PHQ-A], Johnson, Harris, Spitzer & Williams, 2002)	—

Secondary

Measure	Time frame
Secondary endpoints at all follow-up timepoints (at the end of intervention and 6-months follow-up as well as 1- and 2-year follow-up within the ProHEAD Project) include the following: (1) depression symptomatology (Patient Health Questionnaire-9 modified for Adolescents [PHQ-A], Johnson, Harris, Spitzer & Williams, 2002) at all follow-up timepoints; (2) help-seeking attitudes (Inventory of Attitudes Toward Seeking Mental Health Services [IASMHS], Mackenzie, Corey, Knox, Gekoski & Macaulay, 2006) and actual face-to-face help-seeking (General Help-Seeking Questionnaire [GHSQ], Wilson, Deane, Ciarrochi & Rickwood, 2005; Actual Help-Seeking Questionnaire [AHSQ], Rickwood & Braithwaite, 1994) in those with transition to full-threshold depression; (3) adherence to the interventions (measured by participation rates), satisfaction with the interventions (Fragebogen zur Messung der Patientenzufriedenheit [ZUF-8], Schmidt et al. 1989, 1994), and negative effects of online interventions (Inventory for the Assessment of Negative Effects of Psychotherapy [INEP], Ladwig, Rief & Nestoriuc, 2014); (4) depression stigma (Depression Stigma Scale [DSS]; Griffiths, Christensen, Jorm, Evans & Groves, 2004); and (5) utilization and cost of interventions (in conjunction with ProHEAD sub-project 7). In addition, reasons for non-participation will be assessed using an anonymous questionnaire.	—

Measure

Time frame

Secondary endpoints at all follow-up timepoints (at the end of intervention and 6-months follow-up as well as 1- and 2-year follow-up within the ProHEAD Project) include the following: (1) depression symptomatology (Patient Health Questionnaire-9 modified for Adolescents [PHQ-A], Johnson, Harris, Spitzer & Williams, 2002) at all follow-up timepoints; (2) help-seeking attitudes (Inventory of Attitudes Toward Seeking Mental Health Services [IASMHS], Mackenzie, Corey, Knox, Gekoski & Macaulay, 2006) and actual face-to-face help-seeking (General Help-Seeking Questionnaire [GHSQ], Wilson, Deane, Ciarrochi & Rickwood, 2005; Actual Help-Seeking Questionnaire [AHSQ], Rickwood & Braithwaite, 1994) in those with transition to full-threshold depression; (3) adherence to the interventions (measured by participation rates), satisfaction with the interventions (Fragebogen zur Messung der Patientenzufriedenheit [ZUF-8], Schmidt et al. 1989, 1994), and negative effects of online interventions (Inventory for the Assessment of Negative Effects of Psychotherapy [INEP], Ladwig, Rief & Nestoriuc, 2014); (4) depression stigma (Depression Stigma Scale [DSS]; Griffiths, Christensen, Jorm, Evans & Groves, 2004); and (5) utilization and cost of interventions (in conjunction with ProHEAD sub-project 7). In addition, reasons for non-participation will be assessed using an anonymous questionnaire.

—

Countries

Germany

Contacts

Public ContactChristine Rummel-Kluge

Universitätsklinikum Leipzig, Klinik und Poliklinik für Psychiatrie und Psychotherapie

prohead@medizin.uni-leipzig.de034124681

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 4, 2026