D68.00
Conditions
Interventions
Group 1: Current:
Patients with stenotic congenital heart defects (CHD) undergoing cardiac surgery with cardiopulmonary bypass at the Center for Congenital Heart Defects of the Heart and Diabetes Cent
Sponsors
Herz- und Diabeteszentrum Nordrhein-Westfalen Universitätsklinik der Ruhr-Universität Bochum Institut für Laboratoriums- und Transfusionsmedizin
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with stenotic congenital heart defects (CHD) undergoing cardiac surgery with cardiopulmonary bypass at the Center for Congenital Heart Defects of the Heart and Diabetes Center NRW in the period from August 2008 to May 2017. The following CHD were included: valve and vascular stenosis of the aorta and pul-monary artery, coarctation of the aorta, Tetralogy of Fallot, hypertrophic obstructive cardiomyopathy, atrial septal defect, ventricular septal defect and atrioventricular sep-tal defect.
Exclusion criteria
Exclusion criteria: Preoperative antiplatelet therapy (<10 days before surgery), thrombocytopenia (<100*103 *µl-1), coagulation disorder, drugs inducing AVWS, untreated hypothyroidism and administration of von Willebrand factor concentrates or desmopressin (only in the historical cohort)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative drainage volume in % The primary endpoint was perioperative blood loss, which was determined by measuring the chest tube drainage from admission to the paediatric intensive care unit until removal of the chest tube or until the moment of clear and serous drainage. | — |
Secondary
| Measure | Time frame |
|---|---|
| used blood products | — |
Countries
Germany
Contacts
Public ContactIngvild Birschmann
Herz- und Diabeteszentrum Nordrhein-Westfalen Universitätsklinik der Ruhr-Universität Bochum
Outcome results
None listed