Take control! Evaluation of a novel training to improve self-control in tobacco dependence

Take control! Evaluation of a novel training to improve self-control in tobacco dependence - ICT

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

DRKS

Registry ID

DRKS00014652

Enrollment

120

Registered

2018-04-23

Start date

2018-04-24

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tobacco dependence

Interventions

Group 1: Disorder-specific inhibition training (based on the Go-/No-Go-Task, GNGT): Participants will be presented smoking-related and neutral pictures in fully randomized order. Participants are inst

blue frame: no-go trials). The training should be performed daily over 4 weeks. In total, it consists of 320 trials. Group 3: Control training (Placebo): Participants are presented smoking-related and

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: - age 18-70 years - CO = 10 ppm - FTND = 3 - non-usage of nicotine replacement therapy (NRT) and e-cigarettes - no pharmacological or psychotherapeutic smoking cessation intervention - non-usage NRT, e-cigarettes and other smoking cessation interventions during study participation

Exclusion criteria

Exclusion criteria: - severe neurological disorder (Parkinson, mulitple sclerosis) - severe psychiatric disorder (e.g. bipolar disorder, schizophrenia) - Acute Suicidality - Substance dependence (except tobacco) within the last 12 months - pregnancy or nursing - insuffucient knowledge of German language

Design outcomes

Primary

Measure	Time frame
Clinical Outcome: Reduction of daily cigarette consumption from pre to post (Interval:4 Wochen). Process: Improvement of inhibition/self-control from pre to post (interval: 4 weeks). Both general and disorder-specific inhibition will be used.	—

Secondary

Measure	Time frame
1. Efficacy Secondary analyses consider whether the training reduce tobacco dependence (CO, Fagerström Test for Nicotine Dependence, Brief Questionnaire of Smoking Urges) at post and 3-month follow-up. For analyses, in a first step both groups receiving the inhibition training are collapsed and compared to control groups. If the trainings are more effective, it will be investigated whether the general and the disorder-specific training differ in their efficacy. If no differences emerge in the first analysis (inhibtion vs. control groups), the group receiving the disorder-specific training will be compared to control groups. 2. Working mechanisms: Additionally, possible working mechanisms will be investigated. More specifially, it will be investigated whether effects of the training(s) result from (a) improvement of strategic response inhibition (as assessed with the Stop-Signal Task), (b) improvement of automatic response inhibtion (as assessed with the GNGT), or (c) stimulus devaluation (as assessed with the Implicit Association Test) Furthermore, it will be investigated whether the trainings generalized to other implicit processes such as implicit behavioral tendencies (as assessed with the Approach-Avoidance Task). Last, it will be investigated whether the training exert positive effects on impulsivity (as assessed with the Barratt-Impulsiveness Scale 15).	—

Measure

Time frame

1. Efficacy Secondary analyses consider whether the training reduce tobacco dependence (CO, Fagerström Test for Nicotine Dependence, Brief Questionnaire of Smoking Urges) at post and 3-month follow-up. For analyses, in a first step both groups receiving the inhibition training are collapsed and compared to control groups. If the trainings are more effective, it will be investigated whether the general and the disorder-specific training differ in their efficacy. If no differences emerge in the first analysis (inhibtion vs. control groups), the group receiving the disorder-specific training will be compared to control groups. 2. Working mechanisms: Additionally, possible working mechanisms will be investigated. More specifially, it will be investigated whether effects of the training(s) result from (a) improvement of strategic response inhibition (as assessed with the Stop-Signal Task), (b) improvement of automatic response inhibtion (as assessed with the GNGT), or (c) stimulus devaluation (as assessed with the Implicit Association Test) Furthermore, it will be investigated whether the trainings generalized to other implicit processes such as implicit behavioral tendencies (as assessed with the Approach-Avoidance Task). Last, it will be investigated whether the training exert positive effects on impulsivity (as assessed with the Barratt-Impulsiveness Scale 15).

—

Countries

Germany

Contacts

Public ContactCharlotte Wittekind

Ludwig-Maximilians-Universität München Lehrstuhl für Klinische Psychologie und Psychotherapie

charlotte.wittekind@lmu.de00438921802274

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 6, 2026