Detection of circadian variations in corneal thickness in patients with Fuchs endothelial dystrophy (FED)

Detection of circadian variations in corneal thickness in patients with Fuchs endothelial dystrophy (FED) - FED

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00014651

Enrollment

Registered

2018-04-24

Start date

2018-05-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H18.5

Interventions

Group 1: 30 patients with FED should receive a morning and afternoon vision assessment. Also in the morning and in the afternoon, a corneal pachymetry should be performed in parallel. For better compa

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 60 consecutive adult patients with Fuchs endothelial dystrophy (FED).

Exclusion criteria

Exclusion criteria: Non-existence of written consent, language problems, mental retardation, non-existence of a majority.

Design outcomes

Primary

Measure	Time frame
The primary endpoint will be reached if a successful data collection could take place at two measurement points on the day of the investigation. Planned data collection: The patient should receive a non-invasive determination of the endothelial cell count (Tomey EM 3000, Tomey, Itabashi, Japan), a determination of the central, corrected visual acuity as well as the thickness of the cornea (Pentacam®, OCULUS, Wezlar, Germany ) in the morning (8 o'clock) and in the afternoon (15 o'clock).	—

Measure

Time frame

The primary endpoint will be reached if a successful data collection could take place at two measurement points on the day of the investigation. Planned data collection: The patient should receive a non-invasive determination of the endothelial cell count (Tomey EM 3000, Tomey, Itabashi, Japan), a determination of the central, corrected visual acuity as well as the thickness of the cornea (Pentacam®, OCULUS, Wezlar, Germany ) in the morning (8 o'clock) and in the afternoon (15 o'clock).

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Countries

Germany

Contacts

Public ContactNiklas Loreck

Augenklinik Uni Köln

nloreck@gmail.com01797347844

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026