Multimodal characterization of inflammatory processes in myocarditis by combined [18F]FDG-PET/MRT

Multimodal characterization of inflammatory processes in myocarditis by combined [18F]FDG-PET/MRT - GK-PET/MR Tü-20

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00014634

Enrollment

150

Registered

2018-06-21

Start date

2018-05-09

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I40 I41

Interventions

Group 1: [18F]FDG-PET/MRT of the heart including MR-testsequences myocardial T1/T2-mapping and motion correction

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients with clinical proved or suspected inflammation of the myocardium, warrant clinical indication for a [18F]FDG-PET examination, age: =18 years, written informed consent.

Exclusion criteria

Exclusion criteria: Pregnant and/or breast feeding women, contra-indication for a MR-examination, contra-indication for gadolinium-based contrast agend, adiposities with >150 kg body weight limited capacity to consent.

Design outcomes

Primary

Measure	Time frame
Correlation of functional MR-parameters (particularly T1/T2-mapping) and [18F]FDG-PET with spatial separated tissue characterizations of the myocarditis during PET/MRT.	—

Secondary

Measure	Time frame
Application of a MR-based PET-motion correction to improve the spatial accuracy and image quality of the PET acquisition. establishment of a workflow for heart PET/MRT, improvement of patient’s comfort. Differentiation of inflammation into active vs. healed.	—

Countries

Germany

Contacts

Public ContactSimon Greulich

Universitätsklinikum Tübingen, Innere Medizin III, Kardiologie & Kreislauferkrankungen

simon.greulich@med.uni-tuebingen.de07071-2968888

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026