O14.9 P02
Conditions
Interventions
Group 1: single measurement of PlGF (placental growth factor) and PAPP-A (Pregnancy Associated Plasma Protein-A) at 11+0 to 13+6 weeks of gestation in healthy singleton pregnancies. Ethnicity, smoking
Sponsors
Institute for Prenatal Health
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: normal singleton pregnancy of women age 18 or older between 11+0 and 13+6 weeks of gestation
Exclusion criteria
Exclusion criteria: - fetuses with morphological malformations or aneuploidies - necessity of drug treatment of hypertension, or rheumatic diseases - taking ASS at any time during the pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delivery (control group) oder (pre-eclampsia group) - protein excretion 2+ (60mg/dl) or - systolic blood pressure with two consecutive measurements at intervals of 2-7 days of 140 mm Hg or - diastolic blood pressure with two consecutive measurements at intervals of 2-7 days of 90 mm Hg or - clinical signs of HELLP syndrome | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome is to validate published data about the distribution of PAPP-A and PlGF | — |
Countries
Germany
Contacts
Public ContactPeter Schmidt
Medizinische Hochschule Hannover, Frauenarztpraxis Bahnhofstraße
Outcome results
None listed