G35.2 G35.3
Conditions
Interventions
Group 1: transcranial direct current stimulation (tDCS) in week 1 on day 1, 3 and 5 for 15 min after motor training
Group 2: Sham
Sponsors
Universitätsklinikum Leipzig/Medizinische Fakultät Leipzig
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 18-60 yrs, Primary or secondary progressive MS (McDonald 2010), EDSS 0.0-6.0, no relapses within 1 year before randomisation/baseline, righthandedness, written informed consent
Exclusion criteria
Exclusion criteria: (semi-) professional musicians, professional typist (typewriting), psychotropic medication within last 3 month before Screening, corticosteroids within 8 weeks before Screening, signs for acute relapse, begin of disease modifying therapy with ongoing side effects, active psychiatric illness, depressive symptoms with BDI>17 Points, drug abuse within 1 year before Screening, pregnancy or lactation, current participation in another clinical study, contra indications for application of transcranial magnet or direct current stimulation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Performance index (composite to integrate speed and accuracy performance) at the beginnung of week 2 after training for three times with subsequent tDCS/sham in week 1 | — |
Secondary
| Measure | Time frame |
|---|---|
| 9-hole-peg-test of dominant right hand at the beginning of week 2 | — |
Countries
Germany
Contacts
Public ContactMuriel Stoppe
Universitätsklinikum Leipzig, Klinik und Poliklinik für Neurologie
Outcome results
None listed