K75.8 E66.0
Conditions
Interventions
Group 1: Intervention group:
A blood sample, an abdomen-ultrasound and fibro-scan, stool sample will be performed at different points of the 12 months timeline: pre-operative, 3/6/12 Monate post-opera
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: all patients with confirmed diagnosis of metabolic syndrome, age = 18 years, which undergo a bariatric-surgical operation for a clinical indication
Exclusion criteria
Exclusion criteria: all patients with a relevant liver disease except NADLD or NASH, other life-threatening conditions, pregnant women, alcohol abuse (>30g for men, >20g for women), known drug abuse or participation in drug substitution program, weight loss > 5% 6 months prior to study inclusion, inability to consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Definition of the composition of the T cell immune response in the liver, the fatty tissue and the peripheral blood in patients with metabolic syndrome and/or NAFLD. Correlation of these results with the incident of the disease, the disease activity and the progress of the disease. | — |
Secondary
| Measure | Time frame |
|---|---|
| None defined. | — |
Countries
Germany
Contacts
Public ContactRafael Käser
Universitätsklinikum Freiburg
Outcome results
None listed