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Monoenergetic extrapolation to reduce the use of contrast agent in dual-energy computed tomography

Monoenergetic extrapolation to reduce the use of contrast agent in dual-energy computed tomography - DECT/KM

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00014359
Enrollment
255
Registered
2018-08-16
Start date
2018-08-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

OPS: 3-226 CT of the pelvis with contrast agent OPS: 3-222 CT of the thorax with contrast agent OPS: 3-225 CT of the abdomen with contrast agent

Interventions

Group 1: Evaluation of image quality using modern monoenergetic postprocessing algorithms under reduced contrast agent dose. 90% of contrast agent dose compared to standard protocol Group 2: Evaluatio

Sponsors

Uniklinikum Tübingen, Abteilung f. Diagnostische und Interventionelle Radiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Clinical indication for a CT scan of the pelvic / leg area, thorax or abdomen Presence of all necessary laboratory parameters (creatinine / GFR, thyroid values ??[TSH, possibly fT3 and fT4]) Age =18 years written consent of the patient

Exclusion criteria

Exclusion criteria: non-consenting patients, pregnant women, Contraindication to iodinated contrast media, Compromised vein conditions

Design outcomes

Secondary

MeasureTime frame
Lowering the rate of side effects / complication rate in the administration of iodine-containing contrast agent

Primary

MeasureTime frame
Determination of the minimum KM dose with which a diagnostic image quality can be achieved in the DECT-CT by monoenergetic post-processing

Countries

Germany

Contacts

Public ContactMalte Niklas Bongers

Abteilung für Diagnostische und Interventionelle Radiologie, Hoppe-Seyler-Str. 3, 72072 Tübingen

malte.bongers@med.uni-tuebingen.de07071- 29 82087

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026