C54.1 C53
Conditions
Interventions
Group 1: Observational group: patients with endometrial or cervical cancer having different methods for the analysis of SLN (sentinel lymph nodes).
Goal of this prospective observational trial is to c
Sponsors
Universitätsklinikum Tübingen
Eligibility
Sex/Gender
Female
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Patients with cervical cancer or endometrial cancer with a clinical indication for PET/MRT-examination for i) primary staging or re-staging in advanced disease, ii) unclear diagnosis based on conventional imaging procedures for op-planning, iii) pre-op exclusion of pelvine metastasis in case of pelvine relapse - Age: =18 years - Written informent consent
Exclusion criteria
Exclusion criteria: - Histologic type of carcinosarcoma or other rare entities - Precnancy or breast feeding women - No written informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation of different imaging methods for the detection of SLN (SPECT/CT, intra-op staining methods, PET/MRT) – among each other and in correlation to gold standard (immunohistological analysis) – for the pre-op localization of tumor-positive / tumor-negative SLN | — |
Secondary
| Measure | Time frame |
|---|---|
| What is the predictive value of the combination of different imaging methods for tumor-positive SLN? To do so: evaluation of sensitivity, specificity, accuracy as well as positive/negative predictive value of single imaging methods or combinations thereof for the detection of positive/negative SLN in patients with endometrial or cervical cancer – compared to gold standard (histopathological analyses of SLN). | — |
Countries
Germany
Contacts
Public ContactSara Brucker
Universitätsklinikum Tübingen, Frauenklinik
Outcome results
None listed