H35.7
Conditions
Interventions
Group 1: Subthreshold laser treatment with endpoint management, treatment can be repeated up to every 3 months. Study visits take place at baseline and at months 1, 2, 3, 6, 9, 12 and include the foll
Sponsors
Augenklinik der Ludwig-Maximilians Universität München
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age = 18 years BCVA better than 0,05 Subject is generally healthy and able to give informed consent. Diagnosis of CRCS confirmed by retinal specialist Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
Exclusion criteria
Exclusion criteria: Any other macular disease with possibility of developing subretinal fluid: vitreomacular traction syndrome, epiretinal membranes, age-related macular degeneration, diabetic retinopathy, choroidal neovascularization, uveitis Ocular surgery for 6 months preceding the study Previous intravitreal injections of anti-VEGF, steroids within 6 months preceding the study Previous macular laser treatment or photodynamic therapy within 3 months preceding the study Present ocular infection or clinically significant inflammation Patient is not able to cooperate or has any other medical or psychological condition that prohibits him from regular follow-up Kidney failure or dialysis Allergy to fluorescein Participation in a clinical trial in the 30 days preceding the study Planned intraocular surgery within one 12 months Women: Pregnancy or currently breast-feeding History of systemic or topical corticosteroid use within last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average reduction of central retinal thickness as measured by spectral domain optical coherence tomography (SD OCT) after 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in Visual acuity ("Early Treatment of Diabetic Retinopathy Study"- charts, best corrected visual acuity), Macular function (MAIA® microperimetry) and central choroidal thickness (spectraldomain optical coherence tomography) after 6 and 12 months. Rate of total subretinal fluid resorption and recurrence rate after 6 and 12 months. | — |
Countries
Germany
Contacts
Public ContactBenedikt Schworm
Augenklinik der Ludwig-Maximilians Universität München
Outcome results
None listed