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Effect of acute endurance and resistance exercise on the Tryptophan-Kynurenine Pathway

Effect of acute endurance and resistance exercise on the Tryptophan-Kynurenine Pathway

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00014286
Enrollment
24
Registered
2018-04-05
Start date
2018-04-09
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IMMUNESYSTEM

Interventions

Group 1: The first arm describes the conduction of a single bout of 45-minute endurance exercise on a cycle ergometer. Following a three-minute warm-up period with 50 Watts, the trainings period is in

Sponsors

Institute for Cardiovascular Research and Sports Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: healthy ,sport students

Exclusion criteria

Exclusion criteria: Operated, under strong medication, performance athletes

Design outcomes

Primary

MeasureTime frame
The primary outcome of this study is the amino acid Tryptophan, its metabolites Kynurenine and Kynurenine Acid as well as the cytokines Interleukin-6 and Interferon-?. The determination of the outcomes is conducted through the blood analysis before (T0), immediately after (T1) and one hour after (T2) the completion of the exercise sessions.

Secondary

MeasureTime frame
As secondary outcomes, blood and lipid profile as well as PBMCs (Peripheral Blood Mononuclear Cells) will be measured before (T0), immediately after (T1) and one hour after (T2) the completion of the exercise sessions.

Countries

Germany

Contacts

Public ContactChristina Koliamitra

Institute for Cardiovascular Research and Sports Medicine

c.koliamitra@dshs-koeln.de(+49) 0221/4982 5450

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026