healthy subjects
Conditions
Interventions
Group 1: Design
Single center one dose kinetic study at the Muenster university hospital, Germany
No randomisation, placebo-control and blinding of the medical staff or subjects.
Description
The sub
Sponsors
Universitätsklinikum Münster
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 18 - 60 years, male/female, no intake of drugs (except contraceptives), no metabolic disease (like Diabetes Typ I / II), no health impairment, no mental or linguitic limitations, no low-carb, vegane, or other nutrition form with a low carbohydrate intake, accepting of informed consent
Exclusion criteria
Exclusion criteria: intake of nutritional supplements with effect on fatty acid metabolism (like MCT), pregnancy and breast feeding period, participation in other studies at the same time, metabolic disease, chronical disease, daily nutrition with low intake of carbohydrates (< 50 E%), blood donation in the last three months, intolerance against flavors and sweeteners (like stevia), psychological illness (depression, schizophrenia, etc.), severe diseases (like cancer), intake of drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ß-hydroxybutyrate (mmol/L) in serum at t0 (baseline) and tmax (primary outcome). Measuring over a period of 6 hours every 30 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| tolerability (self documentation of the subjects, during intervention time), sensory interview (description of taste, odor, color during intake of test solution), blood parameters: glucose (every 30 minutes over 6 h), blood gas analysis (t0, after 3 h and 6 h [end]): sodium, potassium, calcium, pH, hydrogencarbonate | — |
Countries
Germany
Contacts
Public ContactTobias Fischer
FH Münster
Outcome results
None listed