Neurobiology of Repetitive Negative Thinking: Worry and Rumination in Healthy Controls

Neurobiology of Repetitive Negative Thinking: Worry and Rumination in Healthy Controls - WORU

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00014084

Enrollment

Registered

2018-04-10

Start date

2018-04-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rumination & worry

Interventions

Group 1: Healthy Controls - fMRI paradigm regarding rumination/worry (2x10 min. resting state before and after paradigm

paradigm consisting of personalized worry/rumination topics

comparison task alternative uses test

20 min.)

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adequate speech comprehension (German)

Exclusion criteria

Exclusion criteria: Psychiatric or neurological (pre-) conditions, pregnancy, MR exclusion criteria (intracorporal pieces of metal, braces, magnetic implants, non-removable piercings, extensive tattoos), uncorrected defective vision

Design outcomes

Primary

Measure	Time frame
BOLD-signal during the fMRI-paradigm regarding repetitive negative thinking (6x60 seconds worry, 6x60 seconds rumination) & BOLD-Signal during resting state (2x600 seconds)	—

Secondary

Measure	Time frame
Questionnaires regarding worry/rumination before the fMRI-session, personality variables regarding worry/rumination (tendencies, meta-cognitions)	—

Countries

Germany

Contacts

Public ContactAnya Pedersen

Klinische Psychologie und Psychotherapie am Institut für Psychologie, Christian-Albrechts-Universität zu Kiel

dfigura@psychologie.uni-kiel.de0431-880-3617

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026