Mediators of change within a cognitive and a mindfulness-based intervention for depression

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00014069

Enrollment

100

Registered

2018-02-26

Start date

2014-02-24

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32 F33

Interventions

Group 1: Cognitive intervention: Participants were familiarized with the cognitive model and it was emphasized that the connection between an activating event and its (emotional) consequences depends

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: To be included, participants had to meet the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV; American Psychiatric Association, 1994) criteria for a current episode of MDD.

Exclusion criteria

Exclusion criteria: Participants were excluded if they met one of the following criteria: a bipolar disorder, a lifetime psychotic disorder, a current alcohol or substance abuse or addiction, active suicidal ideations, a change in anti-depressive medication within the last six weeks preceding the study or a current psychotherapy. Diagnostic criteria were derived from the German version of the Structured Clinical Interview for DSM-IV (SCID I; Wittchen, Wunderlich, Gruschwitz, & Zaudig, 1997).

Design outcomes

Primary

Measure	Time frame
Changes in automatic thoughts (Automatic Thoughts Questionnaire-Revised (ATQ-R); German version: Pössel, Seemann, & Hautzinger, 2005), dysfunctional attitudes (Dysfunctional Attitude Scale (DAS); German short version: Joormann, 2004), mindfulness skills (Kentucky Inventory of Mindfulness Skills (KIMS); German version: Ströhle, Nachtigall, Michalak & Heidenreich, 2010), positive and negative affect (Positive and Negative Affect Schedule (PANAS); German version: Krohne, Egloff, Kohlmann & Tausch, 1996), pleasentness of activity (4 Items, based on a study by Geschwind, Peeters, Drukker, van Os & Wichers, 2011) Th ATQ-R and DAS were assessed pre-treatment as well as every second day (= 7 measurements). The KIMS was measured pre- and post-treatment as well as after one week. Affect and pleasentness of activity were assessed evey day (=14 measurements).	—

Measure

Time frame

Changes in automatic thoughts (Automatic Thoughts Questionnaire-Revised (ATQ-R); German version: Pössel, Seemann, & Hautzinger, 2005), dysfunctional attitudes (Dysfunctional Attitude Scale (DAS); German short version: Joormann, 2004), mindfulness skills (Kentucky Inventory of Mindfulness Skills (KIMS); German version: Ströhle, Nachtigall, Michalak & Heidenreich, 2010), positive and negative affect (Positive and Negative Affect Schedule (PANAS); German version: Krohne, Egloff, Kohlmann & Tausch, 1996), pleasentness of activity (4 Items, based on a study by Geschwind, Peeters, Drukker, van Os & Wichers, 2011) Th ATQ-R and DAS were assessed pre-treatment as well as every second day (= 7 measurements). The KIMS was measured pre- and post-treatment as well as after one week. Affect and pleasentness of activity were assessed evey day (=14 measurements).

—

Secondary

Measure	Time frame
changes in depressive symptoms (German version of BDI-II: Hautzinger, Keller, & Kuehner, 2006). Depressive Symptoms were measured pre- and post-treatment as well as every second day (=8 measurements).	—

Countries

Germany

Contacts

Public ContactChristine Hofheinz

Universität Hildesheim,Institut für Psychologie

hofheinz@uni-hildesheim.de05121-88310994

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026