healthy controls
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - age >18 years - written and informed consent - suitability for exercise test (Physical Activity Readiness Questionnaire)
Exclusion criteria
Exclusion criteria: - significant pre-existing cardiological or pulmonal disease as well as significant diseases of the musculoskeletal system -absolute contraindication for 5-aminolevulinic-acid-patch (for COMET measurement): allergy to 5-aminolevulinic-acid-hydrocholride, acrylic adhesives, pigmented polyethylene or aluminized polyester - porphyria, skin disease which are caused or aggravated by sun light, increased sensitivity to sun light - pregnancy/breastfeeding - participation in another intervention study - previous participation in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in mitoPO2 and mitoVO2 between second baseline-measurement (T2) und first measurement after exercise (T3) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of stability of mitoPO2 and mitoVO2 between T1 and T2 as well as between baseline-measurements (T1, T2) and T4 Exploratory analysis on effects of age and sex on mitoPO2 and mitoVO2 at T1, T2 and T4 Exploratory analysis on effects of the bioelectrical impedance analysis parameters on mitoPO2 and mitoVO2 at T1, T2 and T4 Data collection for the methodical validation of the contactless assessment of oxygen saturation. | — |
Countries
Germany
Contacts
NWG Translational Septomics, Zentrum für Innovationskompetenz (ZKS) Septomics, Universitätsklinikum Jena