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A pilot study on exercise induced changes in cellular oxygen metabolism measured by the Cellular Oxygen METabolism Monitor (COMET)

A pilot study on exercise induced changes in cellular oxygen metabolism measured by the Cellular Oxygen METabolism Monitor (COMET) - PICOMET

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00014033
Enrollment
40
Registered
2018-02-15
Start date
2018-02-12
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy controls

Interventions

Group 1: T0 Written and informed consent 10 minutes rest Start Holter-Electrocardiography, preparation bioelectrical impedance analysis T1 COMET, pulse/camera based oximetry, blood pressure, bioelec

Sponsors

NWG Translational Septomics, Zentrum für Innovationskomepetenz (ZIK) Septomics, Universitätklinikum Jena
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: - age >18 years - written and informed consent - suitability for exercise test (Physical Activity Readiness Questionnaire)

Exclusion criteria

Exclusion criteria: - significant pre-existing cardiological or pulmonal disease as well as significant diseases of the musculoskeletal system -absolute contraindication for 5-aminolevulinic-acid-patch (for COMET measurement): allergy to 5-aminolevulinic-acid-hydrocholride, acrylic adhesives, pigmented polyethylene or aluminized polyester - porphyria, skin disease which are caused or aggravated by sun light, increased sensitivity to sun light - pregnancy/breastfeeding - participation in another intervention study - previous participation in this study

Design outcomes

Primary

MeasureTime frame
Differences in mitoPO2 and mitoVO2 between second baseline-measurement (T2) und first measurement after exercise (T3)

Secondary

MeasureTime frame
Evaluation of stability of mitoPO2 and mitoVO2 between T1 and T2 as well as between baseline-measurements (T1, T2) and T4 Exploratory analysis on effects of age and sex on mitoPO2 and mitoVO2 at T1, T2 and T4 Exploratory analysis on effects of the bioelectrical impedance analysis parameters on mitoPO2 and mitoVO2 at T1, T2 and T4 Data collection for the methodical validation of the contactless assessment of oxygen saturation.

Countries

Germany

Contacts

Public ContactPhilipp Baumbach

NWG Translational Septomics, Zentrum für Innovationskompetenz (ZKS) Septomics, Universitätsklinikum Jena

Philipp.Baumbach@med.uni-jena.de+49-3641-9-325-798

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026