Evaluation of the treatment standard: Treatment of severe acute lung injury by extracorporeal membrane oxygenation

Conditions

severe acute respiratory distress syndrome

Christoph Boesing, Laura V. Schaefer, Peter T. Graf, Paolo Pelosi, Patrícia R. M. Rocco et al. (7 authors)

Journal of Critical Care2023-09-085 citations

10.1016/j.jcrc.2023.154406

Ultraprotective versus apneic ventilation in acute respiratory distress syndrome patients with extracorporeal membrane oxygenation: a physiological study.

Graf PT, Boesing C, Brumm I, Biehler J, Müller KW, Thiel M, Pelosi P, Rocco PRM, Luecke T, Krebs J.

2022-03-0710 citations

10.1186/s40560-022-00604-9

Interventions

Group 1: Under a seized tissue oxygenation and CO2- elimination by extracorporeal membrane oxygenation, the individually suitable background ventilation as well as the individually suitable PEEP press

Eligibility

Sex/Gender

All

Age

16 Years to 99 Years

Inclusion criteria

Inclusion criteria: severe primary and secondary ARDS with curative therapy option, Horrowitz index 16 years

Exclusion criteria

Exclusion criteria: prolonged malignant disease, pulmonary fibrosis, prolonged invasive ventilation> 14 days, Bone marrow transplantation, biological age> 75 years, lack of consent to the study

Design outcomes

Primary

Measure	Time frame
Effects of individually suitable background ventilation and individually suitable PEEP pressure during extracorporeal membrane oxygenation on tissue oxygenation (acid-base balance, arterial-, mixed venous-, venous-, preoxy- and postoxy gas exchange) as well as cardiac output and catecholamine requirement	—

Countries

Germany

Contacts

Public ContactJoerg Krebs

Universitätsmedizin Mannheim

joerg.krebs@umm.de0621-3832415

Outcome results

None listed