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Determination of the diagnostic accuracy of capnovolumetry for the detection of airway obstruction

Determination of the diagnostic accuracy of capnovolumetry for the detection of airway obstruction

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00013935
Enrollment
1280
Registered
2018-03-01
Start date
2018-02-12
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R94.2

Interventions

Group 1: Adult patients coming for diagnostic investigation or routine follow-up into the private practice of pneumologists (centre for pneumonology, oncology and sleep medicine at the Diakonissenhaus

Sponsors

Klinikum rechts der Isar, Institut für Allgemeinmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Adult patients - who confirm their participation in the study in written form and - who will obtain a routine lung function testing

Exclusion criteria

Exclusion criteria: - missing informed consent form - age under 18 years - deficient knowledge of the German language inhibiting the understanding of the sense of the study

Design outcomes

Primary

MeasureTime frame
Primary Outcome: - specificity - sensitivity - positive and negative predictive value of the quotient of ascending slopes (SIII / SII) at a cut-off-value = 0.10 for the detection of an existing airway obstruction In comparison with bodyplethysmograpy results (indicating airway obstruction FEV1 < 70% of normal, pathological sRAW / RAW)

Secondary

MeasureTime frame
Secondary outcome: - sensitivity - specificity and - predictive values of other ascending slope quotients that can be identified with a ROC-analysis. Moreover the correlation between capnovolumetry and the parameters of the bodyplethysmography will be investigated in an exploratory manner in order to determine a possible additional benefit in the detection of emphysema and increased dead space volume.

Countries

Germany

Contacts

Public ContactAntonius Schneider

Klinikum rechts der Isar der TU MünchenInstitut für Allgemeinmedizin

antonius.schneider@mri.tum.de0049 (0)89 614 65 89 13

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 3, 2026