Pilot: Implementation of an experimentalisolated lung perfusion model on resected human lobes for investigation of (patho-)physiologic mechanisms and the application of new therapeutic strategies

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013927

Enrollment

Registered

2018-02-14

Start date

2018-03-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

surgically resected pulmonary lobe C34.9 C78.0

Interventions

Group 1: Pilot Study, no Group assignment Prolongued lung preservation by means of isolated lung Perfusion of surgically resected human lobes

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - surgical lung resection

Exclusion criteria

Exclusion criteria: - lack of informed consent

Design outcomes

Primary

Measure	Time frame
Functional Parameters during Perfusion (Ventilation pressures, Perfusion pressures, Gasexchange) half-hourly to hourly	—

Secondary

Measure	Time frame
half life duration of ILP before decrease of gas exchange (pAo2) below 50% of Initial value	—

Countries

Germany

Contacts

Public ContactAlexis Slama

Universitätsmedizin Essen, Ruhrlandklinik, Abt. f. Thoraxchirurgie

alexis.slama@uk-essen.de+49 (0) 201 / 433-4803

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026