K10.2
Conditions
Interventions
Group 1: PET/MRT examination for patients suspicious for osteomyelitis of the jaw
Sponsors
Universitätsklinikum Tübingen, Radiologische Klinik, Diagnostische & Interventionelle Radiologie
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - patients suspicious for osteomyelitis of the jaw, age: =18 years, situation before surgery, informed consent
Exclusion criteria
Exclusion criteria: Acute other illness such as infection, limited contractual capability, pregnancy, breast feeding women, contra-indication for MRT such as metallic implants, pacemaker etc, high sensitivity to noise or temperature, claustrophobia, contra-indication for MR-contrast agend gadolinium, adipositas (>150 kg body weight).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of diagnostic value of the dynamic PET/MR in regard to determine correct extention and activity of osteomyelities/necrosis of the jaw. Correlation with histopathological data after surgery (gold standard). | — |
Secondary
| Measure | Time frame |
|---|---|
| - Comparism of data from patients receiving bisphosphonate/denosumab therapy or showing osteoradionecrosis to identify pathophysiological differences. - Analysis of functional and metabolic parameters relating to time and cost reduction of diagnostic procedures. - Evaluation of PET/MR data relating to prognostic information for further clinical follow-up. | — |
Countries
Germany
Contacts
Public ContactSebastian Hoefert
Universitätsklinikum Tübingen, Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
Outcome results
None listed