Positive suggestion on audiotape during general anaesthesia to reduce postoperative pain, nausea and recovery time.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013800

Enrollment

400

Registered

2018-01-26

Start date

2018-01-16

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Auditorical Suggestions during general anesthesia

Interventions

Group 1: Auditorical Suggestions via ear speaker during general anesthesia Group 2: Control group gets no auditorical Suggestions but an ear speaker during general anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Surgery duration 1 - 3 hours. Surgery in general anaesthesia under a volatile anaesthetic. Age between 18 and 70 years. Patients at risk of postoperative nausea and vomiting (PONV) measured by an Apfel score =2. ASA Score I-III.

Exclusion criteria

Exclusion criteria: Preoperative chronic pain therapy. Preoperative placement of a regional pain catheter. Significant impairment measured by an ASA score >III. Post-operative ventilation or intensive care therapy. Rejection by the patient.

Design outcomes

Primary

Measure	Time frame
Requirement of pain medication (if patient experiences a pain intensity of NRS = 3) during the first 2 and 24 hours (post-surgery after admission to recovery room)	—

Secondary

Measure	Time frame
- Post-operative pain levels (NRS) at 0 min (admission to PACU), 15 min, 30 min, 45 min, 60 min, 75 min, 90 min, 105 min, 2 hours and 24 hours. - Maximum post-operative pain levels (NRS) within 2- and 24-hours post-surgery (after admission to PACU). - Post-operative nausea and vomiting (PONV) at 2- and 24-hours post-surgery (after admission to PACU). - Requirement of antiemetic medication in presence of post-operative nausea and vomiting (PONV) during the first 2 and 24 hours after surgery (after admission to PACU). - Post-operative comfort at 2- and 24-hours post-surgery (after admission to PACU). - Post-operative anxiety at 2- and 24-hours post-surgery (after admission to PACU). - Post-operative mental orientation grade after extubation, and at 2- and 24-hours post-surgery (after admission to PACU). - Anesthesia wakeup time (time from end of surgery until extubation).	—

Measure

Time frame

- Post-operative pain levels (NRS) at 0 min (admission to PACU), 15 min, 30 min, 45 min, 60 min, 75 min, 90 min, 105 min, 2 hours and 24 hours. - Maximum post-operative pain levels (NRS) within 2- and 24-hours post-surgery (after admission to PACU). - Post-operative nausea and vomiting (PONV) at 2- and 24-hours post-surgery (after admission to PACU). - Requirement of antiemetic medication in presence of post-operative nausea and vomiting (PONV) during the first 2 and 24 hours after surgery (after admission to PACU). - Post-operative comfort at 2- and 24-hours post-surgery (after admission to PACU). - Post-operative anxiety at 2- and 24-hours post-surgery (after admission to PACU). - Post-operative mental orientation grade after extubation, and at 2- and 24-hours post-surgery (after admission to PACU). - Anesthesia wakeup time (time from end of surgery until extubation).

—

Countries

Germany

Contacts

Public ContactGünther Oprea

Klinik für Anästhesiologie, Universitätsklinikum Knappschaftskrankenhaus Bochum GmbH

guenther.oprea@gmx,de0234 299 80017

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 16, 2026