magnesium deficiency healthy volunteers
Conditions
Interventions
Group 1: Each subject has 4 examination days at intervals of one week. The total study duration is therefore 4 weeks. Each subject receives each of the two test products 2 times (duplicate) in a rando
Sponsors
Institut für Lebensmittelwissenschaft und Humanernährung
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: BMI between 18.5-29.9 kg / m², Ability and willingness of study participants to follow the doctor's instructions, written consent of the subjects after detailed oral and written information on the study contents, requirements and risks
Exclusion criteria
Exclusion criteria: Allergy/intolerance to components of the administered test products, Use of nutritional supplements and / or medicines with magnesium, severe chronic diseases (diabetes type I, renal insufficiency, liver diseases, manifest cardiovascular diseases, cancer), diagnosed blood coagulation disorders and anticoagulant medication, e.g. Marcumar (except ASS), chronic diseases of the gastrointestinal tract (ulcerative colitis, Crohn's disease, pancreatic insufficiency), regular intake of laxatives, Pregnancy or lactation, Alcohol, drug and / or drug dependence, subjects who are incapable of giving consent, Refusal or withdrawal of consent by the subject, simultaneous participation in another clinical trial or participation within the past 30 days, planned surgery in the next 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnesium excretion with the urine at the time point/period 0, 0-2, 2-4, 4-6, 6-8, 8-12, 12-24 hrs. after ingestion of the test product. | — |
Secondary
| Measure | Time frame |
|---|---|
| Magnesium concentration in serum at time 0 (fasting), 1, 2, 3, 4, 6 and 8 hours after ingestion of the test product. | — |
Countries
Germany
Contacts
Public ContactTheresa Greupner
Institut für Lebensmittelwissenschaft und Humanernährung
Outcome results
None listed