M89.0 G57.9 Z76.9 G57.8 M80 M81
Conditions
Interventions
Group 1: Group 1: Ultrasound-based measurement of bone mineral density in both feet in patients suffering from CRPS (complex regional pain syndrome) or mononeuropathy of a lower extremity (G57.8, G57.
Sponsors
Abteilung für Endokrinologie und DiabetologieMedizinische Klinik Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbHUK RUB
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients suffering from CRPS, which were exposed to prolonged immobilisation or partial weight-bearing due to surgery or due to pain in hip or knee joints or appendicular bones. 2. Control collectives: a. Healthy individuals b. Patients suffering from osteopenia or osteoporosis
Exclusion criteria
Exclusion criteria: Missing informed consent – contraindications for SAHARA measurements (including local infection, skin lesions, hyperalgesia due to mechanical contact, metal implants in situ) – fractures with direct calcaneal affection – bilateral disease – insufficient knowledge of the German language or other problems affecting communication – severe cognitive or psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone mineral density, as determined by ultrasound-based measurement, is unilaterally significantly reduced both in early-stage CRPS and in extensive nerve injury, resulting in significantly increased lateral difference compared to the non-affected side. | — |
Secondary
| Measure | Time frame |
|---|---|
| The lateral difference ob bone mineal densitiy, as determined by ultrasound-based measurement, is larger in CRPS compared to other unilateral diseases. After re-mobilisation an increase in bone mineral density is observed, which is, however, reduced in CRPS compared to other diseases. | — |
Countries
Germany
Contacts
Public ContactJohannes W. Dietrich
Sektion Diabetologie, Endokrinologie und Stoffwechsel, Universitätsklinik St. Josef-Hospital, UK RUB
Outcome results
None listed