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Measurement of intraoral pressure in preterm and term infants during non-invasive ventilation

Measurement of intraoral pressure in preterm and term infants during non-invasive ventilation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00013704
Enrollment
50
Registered
2018-01-09
Start date
2018-01-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

P28.5

Interventions

Group 1: In preterm and term infants receiving nHFT- and CPAP-ventilation, respectively, nasopharyngeal pressure is measured. In addition, confounding factors for example diameter of the nares or move

Sponsors

Universitätsmedizin Göttingen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 4 Months

Inclusion criteria

Inclusion criteria: All term and preterm infants treated in the neonatal intensive care unit and the neonatal intermediate care unit of the Universitätsmedizin Göttingen who require non-invasive ventilatory support, whose parents consented, and are without any exclusion criteria

Exclusion criteria

Exclusion criteria: Poor clinical condition (e.g. sepsis); increased tendency to bleed; anatomical characteristics, that make inserting of a nosogastric tube difficult (e.g. choanal atresia); patients in whom inserting nasogastric tubes was very difficult or who do not tolerate this procedure; colonisation with multiresistent bacteria or infection with noro- or adenovirus

Design outcomes

Primary

MeasureTime frame
What is the correlation between airflow, nasopharyngeal pressure, and biometric parameters of the individual patient during nHFT (Nasal High-Flow Therapy) and nCPAP (nasal Continous Positive Airway Pressure)?

Secondary

MeasureTime frame
What are the confounding factors (diameter of the nares, fixation and size of mask and prongs, leakage, movement of the infant) that influence the pressure in the nasopharynx?

Countries

Germany

Contacts

Public ContactJana Dieks

Universitätsmedizin Göttingen, Abteilung für Pädiatrische Kardiologie und Intensivmedizin mit Neonatologie und Pneumologie

jana.dieks@med.uni-goettingen.de0551 39 0

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026