CERebral Blood flow Evaluation and Regulation by UltraSound to improve neurocognitive outcome after cardiopulmonary bypass

CERebral Blood flow Evaluation and Regulation by UltraSound to improve neurocognitive outcome after cardiopulmonary bypass - CERBERUS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00013583

Enrollment

100

Registered

2018-03-19

Start date

2018-05-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F05.8 U51

Interventions

Group 1: Hemodynamic Management according to standard procedure Group 2: Individualized hemodynamic Management: In case MCA (middle cerebral artery) velocity is higher than baseline reduction of CPB (

Eligibility

Sex/Gender

All

Age

45 Years to No maximum

Inclusion criteria

Inclusion criteria: cardiac surgery with CPB, valve surgery, coronary artery bypass

Exclusion criteria

Exclusion criteria: emergency procedures, aortic arch surgery, hypothermic perfusion <32°C

Design outcomes

Primary

Measure	Time frame
POD on first 3 postoperative days as assessed by the confusion assessment method (CAM) or CAM-ICU test (confusion assessment method for the intensive care unit) on the first 3 postoperative days	—

Secondary

Measure	Time frame
postoperative cognitive deficit on 6. postoperative day as assessed by the 6-item screening test	—

Countries

Germany

Contacts

Public ContactMarcus Thudium

Universitätsklinikum Bonn

marcus.thudium@ukbonn.de+49 22828715109

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026