M84.1
Conditions
Interventions
Group 1: Patients who suffer from defect (2-5cm3) nonunion of the tibia or femur receive standardized Masquelet technique treatment. After information and randomization all patients receive contrast-e
no additional radiographs will be taken. By using a questionnaire preoperatively, and postoperatively after 6 weeks, 3, 12 and 24 months, patients give information on pain (VAS - visual analog scale),
Sponsors
Klinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Heidelberg,Abteilung für UnfallchirurgieProf. Dr. med. Gerhard Schmidmaier
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients of full age and patients who suffer from tibial or femoral non-unions with a bone defect of 2-5 cm3 and receive Masquelet treatment.
Exclusion criteria
Exclusion criteria: - Patients under 18 years of age - Patients who do not agree to participate in the study - Patients receiving an amputation because of persistent infection or extended soft tissue defects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Union achieved one year after surgery by evaluation of x-rays in two planes (defined as cortical bridging of at least three out of four cortices). | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life (SF-12)/ non-union perfusion (CEUS/ DCE-MRI), pain (VAS), union achieved two years after surgery by evaluation of x-rays in two planes (defined as cortical bridging of at least three out of four cortices), revision surgery, postoperative infection, union achieved in CT scan one year after surgery | — |
Countries
Germany
Contacts
Public ContactThomas Ferbert
Zentrum für Orthopädie und Unfallchirurgie, Universitätsklinik Heidelberg
Outcome results
None listed