Determining liver fat content with MRT scans to analyze the effect of liver activity on the basal metabolic rate

Determining liver fat content with MRT scans to analyze the effect of liver activity on the basal metabolic rate - Liver-MRT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00013549

Enrollment

Registered

2017-12-29

Start date

2017-08-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Impact of liver activity on basal metabolic rate

Interventions

Group 1: Liver activity is determined by MRT scans of 32 subjects. Male and female are equally distributed. Furthermore different blood parameters are analyzed, the resting metabolic rate is determine

Eligibility

Sex/Gender

All

Age

40 Years to 65 Years

Inclusion criteria

Inclusion criteria: Written consent form, European; BMI 18-35 kg/m², participation in the enable project Z

Exclusion criteria

Exclusion criteria: missing consent form, active smoker, chronic diseases: chronic infection (e.g. HIV), liver diseases (e.g. HBV, HCV); diabetes mellitus; untreated endocrinologic diseases (e.g. thyrotoxicosis or hypothyroidism); autoimmune disease; heart attack, heart disease, cancer or stroke within the last three years; pacemaker; high blood pressure (>150/95 mmHg); circulatory disorder; kidney dialysis; chronic lung disease; gastric ulcer; Parkinson's disease; severe psychological or neurological disorder within the last three years; blood transfusion; outpatient care; unintended weight loss (>5% in the last three months); Contraindication for MRT: pacemaker; implanted defibrillator; artificial cardiac valve; cardioseal; aneurisma-clips (not MR compatible); implanted magnetic metal part;cochlear implant; metal shiver; shell splinter; acupuncture needle; insulin pump; piercings (non removeable); lung diseases; diseases with the central nervous system; pregnant or breast feeding women; claustrophobia; active participation at other medical trials

Design outcomes

Primary

Measure	Time frame
Identifying the impact of liver actitvity (determined by MRT scans) on the resting metabolic rate (determined by indirect calorimetry).	—

Secondary

Measure	Time frame
Identification of correlation between liver fat content, visceral und subcutanous fat. Visceral and subcutanous fat are determined by MRT scans.	—

Countries

Germany

Contacts

Public ContactGloria-Maria Keppner

Molekulare Ernährungsmedizin Technische Universität München

gloria.keppner@tum.de08161712347

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026